WEDNESDAY, March 3, 2021 (HealthDay Information) — A new examine gives even further evidence that people today with particular blood forms may possibly be much more possible to contract COVID-19.
Particularly, it observed that the new coronavirus (SARS-CoV-2) is notably attracted to the blood team A antigen observed on respiratory cells.
The researchers centered on a protein on the surface of the SARS-CoV-2 virus called the receptor binding domain (RBD), which is the part of the virus that attaches to the host cells. That can make it an vital focus on for scientists hoping to discover how the virus infects people today.
In this laboratory examine, the team assessed how the SARS-CoV-2 RBD interacted with respiratory and pink blood cells in A, B and O blood forms.
The results showed that the SARS-CoV-2 RBD had a sturdy preference for binding to blood team A observed on respiratory cells, but had no preference for blood team A pink blood cells, or other blood teams observed on respiratory or pink cells.
The SARS-CoV-2 RBD’s preference to understand and attach to the blood sort A antigen observed in the lungs of people today with blood sort A may possibly offer perception into the potential connection between blood team A and COVID-19 an infection, according to the authors of the examine. It was printed March 3 in the journal Blood Innovations.
“It is fascinating that the viral RBD only actually prefers the sort of blood team A antigens that are on respiratory cells, which are presumably how the virus is entering most individuals and infecting them,” explained examine writer Dr. Sean Stowell, from Brigham and Women’s Healthcare facility in Boston.
“Blood sort is a obstacle due to the fact it is inherited and not something we can alter,” Stowell explained in a journal news launch. “But if we can greater realize how the virus interacts with blood teams in people today, we may possibly be ready to find new medicines or strategies of prevention.”
These results by yourself cannot entirely explain or predict how coronaviruses would impact individuals of several blood forms, the researchers famous.
“Our observation is not the only mechanism responsible for what we are looking at clinically, but it could make clear some of the impact of blood sort on COVID-19 an infection,” Stowell and his team explained.
A lot more information
The U.S. Centers for Disorder Control and Avoidance has much more on COVID-19.
Resource: Blood Innovations, news launch, March 3, 2021
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