FRIDAY, Sept. four, 2020 (HealthDay News)
Folks with lupus are not at improved hazard of hospitalization from COVID-19 thanks to steroidal remedies they just take to cut down immune process exercise, a new analyze finds.
And a related analyze uncovered that people with inflammatory sorts of arthritis — these types of as rheumatoid arthritis — are not a lot more very likely to be hospitalized with COVID-19 than people without the need of arthritis.
The two reports had been led by scientists at NYU Grossman College of Drugs, in New York Metropolis.
The conclusions “really should reassure most sufferers, in particular people on immunosuppressant treatment, that they are at no higher hazard of owning to be admitted to clinic from COVID-19 than other lupus or arthritis sufferers,” Dr. Ruth Fernandez-Ruiz, co-creator of the reports, reported in an NYU Langone news release.
“Folks with lupus or inflammatory arthritis have the similar hazard aspects for getting seriously unwell from COVID-19 as people without the need of these disorders,” reported Fernandez-Ruiz, a postdoctoral fellow in rheumatology.
Lupus and problems like rheumatoid arthritis, psoriatic arthritis and spondyloarthritis are autoimmune disorders in which the immune process mistakenly attacks a person’s personal tissues. This causes swelling in the joints, skin, kidneys and other components of the body.
The scientists uncovered that lupus sufferers taking immune-suppressing remedies — these types of as mycophenolate mofetil (CellCept) and azathioprine (Imuran) — experienced no higher hazard of hospitalization (fifteen out of 24) than lupus sufferers not utilizing the remedies (nine of seventeen).
In addition, the COVID-19 hospitalization rate for people with inflammatory arthritis (26%) was identical to that of New York Metropolis inhabitants total (25%).
Yet another acquiring was that sufferers taking biologic medicines for arthritis, these types of as adalimumab (Humira) and etanercept (Enbrel), or the antiviral hydroxychloroquine, experienced no higher or decreased hazard of COVID-19 hospitalization than people not taking the medicines.
But sufferers who took steroids termed glucocorticoids, even in delicate doses, experienced a ten moments bigger hazard of COVID-19 hospitalization than people who did not just take steroids. While the acquiring is statistically significant, the study’s compact size may perhaps overestimate the real hazard, the scientists noted.
The reports had been not long ago revealed online in the journal Arthritis and Rheumatology.
— Robert Preidt
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Source: NYU Langone, news release, Aug. 25, 2020